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Clinitians' Biosecurity Network


  
Emergency Resources

 

This Website is supported by funding from the Alfred P. Sloan Foundation.

CBN Report Archive 

Organized by Date | by Topic       

This archive lists CBN Reports published within the past 18 months, organized by date.

  
May 2008

CBN May 2008

Clinicians' Biosecurity Network Report archive for May 2008.
  1. Indonesia Conducts 3-Day Drill of Pandemic Influenza National Response Plan

    Indonesia holds large scale pandemic influenza drill, April 25 - April 27, 2008.
    Thu, 01 May 2008 19:58:31 GMThttp://www.upmc-cbn.org/report_archive/2008/05_May_2008/cbnreport_05012008

  
April 2008

CBN April 2008

Clinicians' Biosecurity Network Report archive for April 2008.
  1. CDC Publishes Report on Meeting of Experts to Update Guidelines for Management of Anthrax (04-14-2008)

    2008: CDC convened subjects matter experts to review and update guidelines for anthrax TX and make consensus recommendations for updating guidelines for PEP, TX, and clinical eval of patients. Read summary of EID's report.
    Mon, Apr 14 2008 19:36:17 GMThttp://www.upmc-cbn.org/report_archive/2008/04_April_2008/cbnreport_04142008.html

    
March 2008

CBN March 2008

Clinicians' Biosecurity Network Report archive for March 2008.
  1. ASPR Makes First Playbook Available (03-28-2008)

    DHHS/ASPR has published the first in a planned series of playbooks addressing response to disasters and other large scale emergencies.
    Fri, Mar 28 2008 21:12:35 GMThttp://www.upmc-cbn.org/report_archive/2008/03_March_2008/cbnreport_03282008.html
  2. The Use of MedKits to Augment Rapid Distribution of Antibiotics after an Anthrax Attack (03-14-2008)

    CBN Report: Following an anthrax attack, many lives could be saved by timely distribution of antibiotics to exposed populations.
    Fri, Mar 14 2008 21:14:54 GMThttp://www.upmc-cbn.org/report_archive/2008/03_March_2008/cbnreport_03142008.html

   
February 2008

CBN February 2008

Clinicians' Biosecurity Network Report archive for February 2008.
  1. California Releases Healthcare Surge Guidelines (02-29-2008)

    On February 19, 2008, the California Department of Public Health released its Standards and Guidelines for Healthcare Surge during Emergencies.
    Fri, Feb 29 2008 20:37:23 GMThttp://www.upmc-cbn.org/report_archive/2008/02_February_2008/cbnreport_022908.html
  2. This Year's flu Season Marked by Vaccine Mismatch in the U.S. and Antiviral Resistance in Europe (02-14-2008)

    CDC reports that this year's flu season in U.S. is more severe than past 2 and that vaccine does not match 43% of strains circulating in U.S. In Europe, there are reports of unexplained oseltamivir resistance.
    Thu, Feb 14 2008 20:55:53 GMThttp://www.upmc-cbn.org/report_archive/2008/02_February_2008/cbnreport_02142008.html
  3. Progress Toward the Development of a Universal Influenza Vaccine (02-01-2008)

    Acambis , a vaccine development company, announced positive preliminary results from two studies of its universal influenza vaccine, ACAM-FLU-A
    Fri, Feb 01 2008 15:26:45 GMThttp://www.upmc-cbn.org/report_archive/2008/02_February_2008/cbnreport_02012008.html

  
January 2008

CBN January 2008

Clinicians' Biosecurity Network Report archive for January 2008.
  1. WHO Update on Human H5N1 Infections (01-18-2008)

    WHO Committee Human Infection with Avian Influenza A (H5N1) Virus provides updated information on human cases of highly pathogenic avian influenza A (H5N1) infection.
    Tue, Jan 22 2008 15:00:49 GMThttp://www.upmc-cbn.org/report_archive/2008/01_January_2008/cbnreport_01182008
  2. Ten Notable Publications of 2007 (01-10-2008)

    Ten notable publications of 2007 from Center for Biosecurity of UPMC.
    Thu, Jan 10 2008 17:47:46 GMThttp://www.upmc-cbn.org/report_archive/2008/01_January_2008/cbnreport_01102008.html

  
December 2007

CBN December 2007

Clinicians' Biosecurity Network Report archive for December 2007.
  1. Evidence for a Heritable Predisposition to Fatal Influenza (12-19-2007)

    CBN Report: A recent study by Albright and colleagues from the University of Utah School of Medicine supports the hypothesis that there exists an inherited predisposition to developing and dying from severe influenza.
    Wed, Dec 19 2007 19:03:07 GMThttp://www.upmc-cbn.org/report_archive/2007/12_December_2007/cbnreport_12192007.html
  2. Estimate of the Financial Effect of a Flu Pandemic on U.S. Hospitals (12-07-2007)

    CBN Report: Center for Biosecurity estimates potential financial impact of a flu pandemic on U.S. hospitals to be approximately $785,000 for average U.S. hospital, and $3.9 billion total for all U.S. hospitals.
    Fri, Dec 07 2007 18:37:25 GMThttp://www.upmc-cbn.org/report_archive/2007/12_December_2007/cbnreport_12072007

   
November 2007

CBN November 2007

Clinicians' Biosecurity Network Report archive for November 2007.
  1. National Academies Report on Boston BSL-4 Laboratory (11-30-2007)

    Yesterday, a National Research Council (NRC) committee deemed an NIH risk analysis for a proposed biocontainment laboratory at Boston University to be "not sound and credible."
    Fri, Nov 30 2007 21:37:00 GMThttp://www.upmc-cbn.org/report_archive/2007/11_November_2007/cbnreport_11302007.html
  2. Oseltamivir Reduces Mortality in Patients Hospitalized with Influenza (11-15-2007)

    CBN Report: In study by McGeer et al, oseltamivir therapy administered to adult patients hospitalized with influenza decreased mortality by almost 80%.
    Thu, Nov 15 2007 13:50:29 GMThttp://www.upmc-cbn.org/report_archive/2007/11_November_2007/cbnreport_11152007.html
  3. Drug-Resistant H5N1 Influenza Viruses May Retain Fitness (11-01-2007)

    CBN Report: A study by Yen of Robert Webster's lab at St. Jude's Hospital reveals that some mutations of H5N1 conferring neuraminidase inhibitor resistance do not lead to loss of viral fitness.
    Thu, Nov 01 2007 19:32:22 GMThttp://www.upmc-cbn.org/report_archive/2007/11_November_2007/cbnreport_11012007.html

   
October 2007

CBN October 2007

Clinicians' Biosecurity Network Report archive for October 2007.
  1. White House Releases HSPD 21: National Strategy for Public Health and Medical Preparedness (10-19-2007)

    This directive addresses preparedness for catastrophic health events . . . which result in a number of ill or injured persons sufficient to overwhelm the capabilities of immediate local and regional emergency response and health care systems.
    Fri, Oct 19 2007 20:50:15 GMThttp://www.upmc-cbn.org/report_archive/2007/10_October_2007/cbnreport_10192007.html
  2. Recent H5N1 Developments (10-15-2007)

    CBN Report: Recent articles shed light on the virulence and pathogenesis of H5N1 and suggest a possible new approach to treatment.
    Mon, Oct 15 2007 14:31:16 GMThttp://www.upmc-cbn.org/report_archive/2007/10_October_2007/cbnreport_10152007.html
  3. IOM Releases Pandemic PPE Report (10-04-2007)

    CBN Report: IOM released a report entitled, "Preparing for an Influenza Pandemic: PPE for Healthcare Workers" stating that the regulatory, certification, and evaluation requirements for PPE need to be revisited to ensure PPE are safe and effective.
    Thu, Oct 04 2007 20:00:05 GMThttp://www.upmc-cbn.org/report_archive/2007/10_October_2007/cbnreport_10042007.html

   
September 2007

CBN September 2007

Clinicians' Biosecurity Network Report archive for September 2007.
  1. HHS Award Multiple Contracts for Anthrax Countermeasures (09-28-2007)

    CBN Report: BARDA awarded contracts for advanced development of anthrax countermeasures Anthim and Valortim. BARDA also awarded a purchase contract for BioThrax anthrax vaccine.
    Mon, Oct 01 2007 13:32:31 GMThttp://www.upmc-cbn.org/report_archive/2007/09_September_2007/cbnreport_09282007.html
  2. Symptoms of Anthrax in Children May be More Varied than Previously Thought (09-14-2007)

    CBN Report: A study published in the September issue of the Archives of Pediatrics & Adolescent Medicine journal represents the "first published synthesis of the literature describing the spectrum of clinical anthrax in children."
    Thu, Sep 13 2007 19:55:00 GMThttp://www.upmc-cbn.org/report_archive/2007/09_September_2007/cbnreport_09142007
  3. New Smallpox Vaccine Licensed (09-07-2007)

    CBN Report: U.S. FDA has approved new smallpox vaccine, ACAM2000, which has been purchased by CDC for strategic national stockpile.
    Fri, Sep 07 2007 13:51:49 GMThttp://www.upmc-cbn.org/report_archive/2007/09_September_2007/cbnreport_09072007.html

  
July 2007

CBN July 2007

Clinicians' Biosecurity Network Report archive for July 2007.
  1. Cytokines and H5N1: Cytokines and H5N1: Still No Clear Answers (7-27-2007)

    CBN Report: A review of the evidence for cytokine storm in H5N1 influenza infection and analysis of 2 recent immune modulation studies in mice.
    Mon, Jul 30 2007 19:28:07 GMThttp://www.upmc-cbn.org/report_archive/2007/07_July_2007/cbnreport_07302007.html
  2. Duration of Influenza A Virus Shedding Longer than Expected (07-17-2007)

    CBN Report: Patients hospitalized with influenza A infection may shed virus beyond the period traditionally considered for infectivity. If so, then current CDC infection control guidelines may be insufficient to prevent nosocomial transmission.
    Tue, Jul 17 2007 18:50:26 GMThttp://www.upmc-cbn.org/report_archive/2007/07_July_2007/cbnreport_07172007

  
June 2007

CBN June 2007

Clinicians' Biosecurity Network Report archive for June 2007.
  1. Highly Lethal MRSA Pneumonia Associated with Influenza (6-21-2007)

    CBN Report: Discussion of MMWR report of outbreak of severe community acquired pneumonia due to MRSA.
    Thu, Jun 21 2007 20:31:56 GMThttp://www.upmc-cbn.org/report_archive/2007/06_June_2007/cbnreport_06212007.html

  
May 2007

CBN May 2007

Clinicians' Biosecurity Network Report archive for May 2007.
  1. OSHA Releases Pandemic Guidance for Healthcare Personnel (05-24-2007)

    CBN Report: OSHA released Pandemic Influenza Preparedness and Response Guidance for Healthcare Workers and Healthcare Employers which provides a concise yet comprehensive overview of the occupational health issues related to hospital pandemic prep.
    Thu, May 24 2007 15:17:19 GMThttp://www.upmc-cbn.org/report_archive/2007/05_May_2007/cbnreport_05242007.html
  2. CDC Issues Interim Guidance for the Use of Facemasks and Respirators in Non-Occupational Settings during an Influenza Pandemic (05-11-2007)

    CBN report: On May 3, 2007, the CDC issued new "Interim Public Health Guidance for the Use of Facemasks and Respirators in Non-Occupational Community Settings during an Influenza Pandemic."
    Fri, May 11 2007 16:20:52 GMThttp://www.upmc-cbn.org/report_archive/2007/05_May_2007/cbnreport_05112007.html
  3. Recent Developments in Respiratory Surge Preparedness (05-03-2007)

    CBN Report: AHRQ released a DVD to teach clinicians basic ventilator management. The NY DOH issued a draft document that proposes an ethical framework and criteria for deciding who receives scarce ventilators.
    Thu, May 03 2007 15:18:23 GMThttp://www.upmc-cbn.org/report_archive/2007/05_May_2007/cbnreport_05032007.html

   
April 2007

CBN April 2007

Clinicians' Biosecurity Network Report archive for April 2007.
  1. New System Promises Access to Prescription Information in a Disaster (04-26-2007)

    CBN Report: Descriptions of new internet-based service, Emergency RxHistory, that will provide prescribers and pharmacists access to the medication histories of patients displaced by a disaster from any internet connection.
    Thu, Apr 26 2007 18:14:22 GMThttp://www.upmc-cbn.org/report_archive/2007/04_April_2007/cbnreport_04262007.html
  2. Prevalence of Drug Resistant Influenza B Viruses: New Findings and Implications (04-13-2007)

    CBN Report: Report on Hatakeyama study [JAMA, 4-4-07] of influenza B viruses partially resistant to neuraminidase inhibitors, suggesting transmission in community or among siblings, with discussion of implications in event of pandemic flu.
    Fri, Apr 13 2007 18:19:13 GMThttp://www.upmc-cbn.org/report_archive/2007/04_April_2007/cbnreport_04132007.html

  
March 2007

CBN March 2007

Clinicians' Biosecurity Network Report archive for March 2007.
  1. Contact Vaccinia (03-27-2007)

    CBN Report: A child developed eczema vaccinatum after contact with his father, who received smallpox vaccine before being deployed to Iraq. This is first report of eczema vaccinatum since smallpox vaccination resumed in 2002.
    Tue, Mar 27 2007 18:49:00 GMThttp://www.upmc-cbn.org/report_archive/2007/03_March_2007/cbnreport_03272007.html
  2. HHS Launches New Website to Guide Medical Care during a Mass Casualty Radiation Incident (03-14-2007)

    CBN Report: On March 8, 2007, HHS Secretary Mike Leavitt announced the launch of a comprehensive web site for health care professionals who may have to provide medical care during a radiation mass casualty incident: http://remm.nlm.gov.
    Wed, Mar 14 2007 16:24:20 GMThttp://www.upmc-cbn.org/report_archive/2007/03_March_2007/cbnreport_03142007.html
  3. Dilution of Smallpox Vaccine, Revisited (03-01-2007)

    CBN Report: Robert Couch and colleagues have conducted additional dilution trials with Dryvax and Wetvax smallpox vaccines, and showed that diluted vaccine not only remains effective, but is associated with reduced vaccine-associated morbidity.
    Thu, Mar 01 2007 16:37:02 GMThttp://www.upmc-cbn.org/report_archive/2007/03_March_2007/cbnreport_03012007.html

  
February 2007

CBN February 2007

Clinicians' Biosecurity Network Report archive for February 2007.
  1. Seasonal Flu Vaccination May Offer Partial Immunity to H5N1 (02-21-2007)

    mice vaccinated with the N1 used in seasonal flu vaccine, had significantly reduced mortality when challenged with H5N1. Some people who have had seasonal influenza vaccination carry antibodies that react to the N1 in the avian H5N1 virus
    Wed, Feb 21 2007 19:48:51 GMThttp://www.upmc-cbn.org/report_archive/2007/02_February_2007/cbnreport_02212007.html
  2. Surgical Masks May Provide Significant Aerosol Protection (02-15-2007)

    Y. Li report the result of his study comparing the in vivo protective performance of surgical masks and N95 respirators: N95 respirators filtered out 97% of a test aerosol while surgical masks did almost as well, filtering out 95% of the aerosol.
    Thu, Feb 15 2007 20:30:39 GMThttp://www.upmc-cbn.org/report_archive/2007/02_February_2007/cbnreport_02152007.html
  3. CDC Releases Interim Planning Guidance for Mitigation of Pandemic Influenza (02-07-2007):

    CBN Report: The CDC released its disease containment strategy for pandemic flu: Interim Pre-pandemic Planning Guidance: Community Strategy for pandemic Influenza Mitigation in the United States.
    Wed, Feb 07 2007 16:14:23 GMThttp://www.upmc-cbn.org/report_archive/2007/02_February_2007/cbnreport_02072007.html

  
January 2007

CBN January 2007

Clinicians' Biosecurity Network Report archive for January 2007.
  1. Partial Anthrax Vaccination Stimulates Significant Antibody Response (01-26-2007)

    Summary of article by Lininger, et al, regarding study of serum anti-protective antigen (PA) concentrations in marines who had been previously vaccinated with the FDA-licensed Anthrax Vaccine Absorbed (AVA).
    Fri, Jan 26 2007 14:40:18 GMThttp://www.upmc-cbn.org/report_archive/2007/01_January_2007/cbnreport_01262007.html
  2. Immunological Responses after Exposure to Anthrax Spores in the U.S. Capitol, 2001 (01-18-2007)

    Review of Doolan's analysis of the humoral and cell-mediated immune responses to B. anthracis among persons exposed and possibly exposed to spores in the U.S. Capitol complex in October 2001, during the anthrax bioterrorist attacks.
    Thu, Jan 18 2007 20:29:27 GMThttp://www.upmc-cbn.org/report_archive/2007/01_January_2007/cbnreport_01182007.html

  
December 2006

CBN December 2006

Clinicians' Biosecurity Network Report archive for December 2006.
  1. Passage of S. 3678-The Pandemic and All-Hazards Preparedness Act (12-20-2006)

    Summary of the details of the passage of S. 3678: The Pandemic and All-Hazards Preparedness Act.
    Wed, Dec 20 2006 17:44:00 GMThttp://www.upmc-cbn.org/report_archive/2006/12_December_2006/cbnreport_122006.html
  2. Efficacy of Gentamicin and Doxycycline in the Treatment of Plague (12-13-2006)

    In an article in the March 1, 2006 issue of Clinical Infectious Diseases, W. Mwengee reports on a prospective, open-label, randomized clinical trial comparing gentamicin and doxycycline for the treatment of naturally-occurring plague in Tanzania.
    Wed, Dec 13 2006 17:08:09 GMThttp://www.upmc-cbn.org/report_archive/2006/12_December_2006/cbnreport_121306.html

   
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