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Clinitians' Biosecurity Network
  
Emergency Resources

 

This Website is supported by funding from the Alfred P. Sloan Foundation.

CBN Report Archive 

Organized by Date | by Topic

This archive lists CBN Reports published within the past 18 months, organized by date.
  

June 2009

CBN June 2009

Clinicians' Biosecurity Network Report archive for June 2009.

  1. H7-subtype Influenza Infections: Pandemic Potential? (06-05-2009)

    However, the pandemic potential of the H7 viruses cannot be overlooked. While they are not nearly as lethal as H5N1, a pandemic need not cause mass lethality to have a significant impact around the globe.
    Fri, 05 Jun 2009 17:48:59 GMThttp://www.upmc-cbn.org/report_archive/2009/06_June_2009/cbnreport_06052009.html

   
May 2009

CBN May 2009

Clinicians' Biosecurity Network Report archive for May 2009.

  1. Hospitals Are Better Prepared for Mass Casualty Disasters (05-08-2009)

    Based on interviews with 133 individuals involved with disaster preparedness in hospitals across the U.S., we found that hospitals are significantly better prepared now than in 2001; much of the improvement is attributable to the HPP.
    Fri, 08 May 2009 15:36:45 GMThttp://www.upmc-cbn.org/report_archive/2009/05_May_2009/cbnreport_05082009.html

  
April 2009

CBN April 2009

Clinicians' Biosecurity Network Report archive for April 2009.

  1. 04-24-2009: Swine Flu Cases Without Swine Exposure

    On 4/21/2009, the CDC described 2 cases of swine flu A (H1N1) infection in Southern CA in April. While both patients recovered uneventfully, the isolated viruses harbor novel genetic characteristics not seen in the U.S. prior to this event.
    Fri, 24 Apr 2009 13:26:22 GMThttp://www.upmc-cbn.org/report_archive/2009/h1n1/04-09_Swine_Flu/cbnreport_SF1_4-24-09_AM.html

  2. Adenovirus 14: An Emerging Threat (04-17-2009)

    The Journal of Infectious Disease has just published 2 papers by teams of researchers describing separate, severe outbreaks of Adenovirus 14 (Ad14), a historically rare serotype of adenovirus that has not been known to cause severe disease.
    Fri, 17 Apr 2009 14:42:36 GMThttp://www.upmc-cbn.org/report_archive/2009/04_April_2009/cbnreport_04172009.html

  3. Oseltamivir Protective Against Influenza-induced Cardiac Events (04-03-2009)

    A new study finds that antiviral therapy can reduce cardiovascular complications following influenza infection in patients with previous cardiac disease.
    Thu, 02 Apr 2009 21:41:56 GMThttp://www.upmc-cbn.org/report_archive/2009/04_April_2009/cbnreport_04032009

   
March 2009

CBN March 2009

Clinicians' Biosecurity Network Report archive for March 2009.

  1. 3rd Generation Smallpox Vaccine LC16m8 Proved Safe and Immunogenic (03-20-2009)

    New JAMA study from Japanese researchers testing LC16m8, tissue-cultured 3rd gen smallpox vaccine. Overall, the vaccine displayed high levels of vaccine take in primary vaccinees and provoked an effective booster response in some revaccinees.
    Fri, 20 Mar 2009 13:31:31 GMThttp://www.upmc-cbn.org/report_archive/2009/03_March_2009/cbnreport_03202009.html

  2. Broad-spectrum Flu Antibodies Characterized (03-06-2009)

    Two teams of researchers recently and simultaneously reported discovery and development of antibodies generated against invariate regions of the influenza virus.
    Fri, 06 Mar 2009 19:10:52 GMThttp://www.upmc-cbn.org/report_archive/2009/03_March_2009/cbnreport_03062009

   
February 2009

CBN Febuary 2009

Clinicians' Biosecurity Network Report archive for February 2009.

  1. Longer Treatment Window for Botulism (02-20-2009)

    Results from a new study published in JID demonstrate the persistence of botulinum toxin in the serum of patients up to 11 days after exposure. The prolonged persistence of toxin allows for admin of anti-toxin as long 12 days after toxin ingestion
    Fri, 20 Feb 2009 17:53:50 GMThttp://www.upmc-cbn.org/report_archive/2009/02_February_2009/cbnreport_02202009.html

  2. Global Avian influenza Panzootic Continues; Some Preparedness Gains Made but Hospitals Remain Vulnerable (02-06-2009)

    Although "bird flu" has not been featured prominently on the evening news of late, the influenza A/H5N1 panzootic continues. And, as has been true since this global outbreak erupted in Thailand and Vietnam, it remains distinctly seasonal in nature.
    Fri, 06 Feb 2009 19:13:05 GMThttp://www.upmc-cbn.org/report_archive/2009/02_February_2009/cbnreport_02062009.html

  
January 2009

CBN January 2009

Clinicians' Biosecurity Network Report archive for January 2009.

  1. Is Airborne Spread of Influenza Possible? (01-22-2009)

    A new study demonstrates that the flu virus is able to remain suspended in the air, thus enabling airborne transmission. This finding suggests the possible need for more stringent infection control measures to forestall spread of flu in hospitals.
    Thu, 22 Jan 2009 20:10:34 GMThttp://www.upmc-cbn.org/report_archive/2009/01_January_2009/cbnreport_01222009.html

  2. Update on Smallpox Vaccine (01-08-2009)

    The 2001 anthrax attacks spurred new vaccine development, and, as a result, there have been several updates to the smallpox vaccine armamentarium, which are reviewed here.
    Fri, 09 Jan 2009 13:42:32 GMThttp://www.upmc-cbn.org/report_archive/2009/01_January_2009/cbnreport_01092009.html

  
December 2008

CBN December 2008

Clinicians' Biosecurity Network Report archive for December 2008.

  1. Update on Personal Protective Equipment (12-19-2008)

    Two recent studies raise questions about best use of PPE and assumptions underlying related current recommendations.
    Fri, 19 Dec 2008 20:43:12 GMThttp://www.upmc-cbn.org/report_archive/2008/12_December_2008/cbnreport_12192008.html

  2. Long-lived Immunity after Smallpox Vaccination (12-05-2008)

    Researchers from NIA have just reported results of a study in which 97% of 209 vaccinated subjects maintained antibody titers for up to 88 years. While promising, these results must be interpreted carefully.
    Fri, 05 Dec 2008 14:05:41 GMThttp://www.upmc-cbn.org/report_archive/2008/12_December_2008/cbnreport_12052008.html

  
November 2008

CBN November 2008

Clinicians' Biosecurity Network Report archive for November 2008.

  1. Modeling Drug Resistant Influenza (11-21-2008)

    In a new mathematical modeling study Brockmann and colleagues report that drug resistant influenza was capable of increasing hospitalization rates by up to 233% in a hypothetical Swiss town of 100,000 inhabitants.
    Mon, 24 Nov 2008 15:44:28 GMThttp://www.upmc-cbn.org/report_archive/2008/11_November_2008/cbnreport_11212008.html

  2. New Arenavirus Identified as Cause of Cluster of Illness and Death in South Africa and Zambia (11-07-2008)

    Through molecular diagnostic techniques, a previously unknown arenavirus has been identified as the etiologic agent responsible for 4 deaths in Africa that occurred in September and October of 2008.
    Fri, 07 Nov 2008 20:12:16 GMThttp://www.upmc-cbn.org/report_archive/2008/11_November_2008/cbnreport_11072008.html

  
October 2008

CBN October 2008

Clinicians' Biosecurity Network Report archive for October 2008.

  1. Rising Staphylococcus aureus Co-infection among Pediatric Influenza Deaths (10-10-2008)

    The results of a study of pediatric flu mortality for 3 flu seasons, by CDC investigators, were published recently. The authors report an increase in the incidence of bacterial co-infection in fatal pediatric flu from 6 to 34 percent in that period.
    Fri, 10 Oct 2008 15:08:11 GMThttp://www.upmc-cbn.org/report_archive/2008/10_October_2008/cbnreport_10092008.html

  
September 2008

CBN September 2008

Clinicians' Biosecurity Network Report archive for September 2008.

  1. Hong Kong Study Finds that Closing Schools May Not Have Helped Slow the Spread of Flu (09-26-2008)

    A new study published in Emerging Infectious Diseases (EID) suggests that Hong Kong�s efforts to close schools for two weeks during the 2008 influenza season may have done little to limit the community-wide spread of influenza.
    Fri, 26 Sep 2008 19:21:39 GMThttp://www.upmc-cbn.org/report_archive/2008/09_September_2008/cbnreport_09262008.html

  2. The Role of Bacterial Pneumonia in Pandemic Influenza (09-12-2008)

    A paper by researchers from NIAID concludes that most deaths during the 1918 flu pandemic appear to have involved bacterial pneumonia rather than purely viral pneumonia. This has important implications for pandemic flu planning now.
    Fri, 12 Sep 2008 20:58:00 GMThttp://www.upmc-cbn.org/report_archive/2008/09_September_2008/cbnreport_09122008.html

 
July 2008

CBN July 2008

Clinicians' Biosecurity Network Report archive for July 2008.

  1. Utility of Antivirals During a Pandemic: Uncertainties Persist (07-30-2008)

    During a pandemic, neuraminidase inhibitors will be the antivirals of choice. But there remains uncertainty about their usefulness because access may be limited, resistance may develop, the dose and duration of treatment is uncertain, etc.
    Wed, 30 Jul 2008 14:39:20 GMThttp://www.upmc-cbn.org/report_archive/2008/07_July_2008/cbnreport_07302008.html

  2. AHRQ Releases Report on Home Healthcare During a Pandemic (07-14-2008)

    CBN Report: On July 8, 2008, the Department of Health and Human Services (HHS) Agency for Healthcare, Research and Quality (AHRQ) released a report on the issues and resources associated with home healthcare during a pandemic.
    Mon, 14 Jul 2008 18:22:10 GMThttp://www.upmc-cbn.org/report_archive/2008/07_July_2008/cbnreport_07142008.html

  
June 2008

CBN June 2008

Clinicians' Biosecurity Network Report archive for June 2008.

  1. Atypical Presentation of Cutaneous Tularemia (06-27-2008)

    Summary of article from 7-01-2008 issue of CID: Byington and colleagues describe cutaneous tularemia in two children who were initially misdiagnosed due to atypical presentations of the disease.
    Fri, 27 Jun 2008 19:53:59 GMThttp://www.upmc-cbn.org/report_archive/2008/06_June_2008/cbnreport_06272008

  2. Evolution of H7 Avian Influenza: Another Pandemic Candidate? (06-06-2008)

    Belser and colleagues report results of study results indicating that some recent strains of avian influenza virus have developed ability to bind to receptors in the human respiratory tract and to spread efficiently between ferrets.
    Fri, 06 Jun 2008 20:26:17 GMThttp://www.upmc-cbn.org/report_archive/2008/06_June_2008/cbnreport_06062008

  
May 2008

CBN May 2008

Clinicians' Biosecurity Network Report archive for May 2008.

  1. OSHA Issues Guidance for Stockpiling Masks and Respirators (05-30-2008)

    OSHA's has proposed new guidelines for determining types, numbers, and costs of masks and respirators to stockpile for use during an influenza pandemic to protect healthcare workers. Guidelines are non-obligatory, but useful planning tool.
    Mon, 02 Jun 2008 20:20:08 GMThttp://www.upmc-cbn.org/report_archive/2008/05_May_2008/cbnreport_05302008.html

  2. Definitive Care for the Critically Ill During a Disaster: Report of the Task Force for Mass Critical Care of the American College of Chest Physicians Released (05-15-2008)

    Reviews preparedness for mass critical care; suggests an alternative approach to provide only essential critical care; specifies types of equipment, staffing, and space required; and suggests a framework for allocation of scarce critical care resources.
    Thu, 15 May 2008 16:18:30 GMThttp://www.upmc-cbn.org/report_archive/2008/05_May_2008/cbnreport_05152008.html

  3. Indonesia Conducts 3-Day Drill of Pandemic Influenza National Response Plan (05-01-2008)

    Indonesia holds large scale pandemic influenza drill, April 25 - April 27, 2008.
    Thu, 01 May 2008 19:58:31 GMThttp://www.upmc-cbn.org/report_archive/2008/05_May_2008/cbnreport_05012008.html

  
April 2008

CBN April 2008

Clinicians' Biosecurity Network Report archive for April 2008.

  1. CDC Publishes Report on Meeting of Experts to Update Guidelines for Management of Anthrax (04-14-2008)

    2008: CDC convened subjects matter experts to review and update guidelines for anthrax TX and make consensus recommendations for updating guidelines for PEP, TX, and clinical eval of patients. Read summary of EID's report.
    Mon, 14 Apr 2008 19:36:17 GMThttp://www.upmc-cbn.org/report_archive/2008/04_April_2008/cbnreport_04142008.html

    
March 2008

CBN March 2008

Clinicians' Biosecurity Network Report archive for March 2008.

  1. ASPR Makes First Playbook Available (03-28-2008)

    DHHS/ASPR has published the first in a planned series of playbooks addressing response to disasters and other large scale emergencies.
    Fri, 28 Mar 2008 19:15:00 GMThttp://www.upmc-cbn.org/report_archive/2008/03_March_2008/cbnreport_03282008.html

  2. The Use of MedKits to Augment Rapid Distribution of Antibiotics after an Anthrax Attack (03-14-2008)

    CBN Report: Following an anthrax attack, many lives could be saved by timely distribution of antibiotics to exposed populations.
    Fri, 14 Mar 2008 21:14:54 GMThttp://www.upmc-cbn.org/report_archive/2008/03_March_2008/cbnreport_03142008.html

   
February 2008

CBN February 2008

Clinicians' Biosecurity Network Report archive for February 2008.

  1. California Releases Healthcare Surge Guidelines (02-29-2008)

    On February 19, 2008, the California Department of Public Health released its Standards and Guidelines for Healthcare Surge during Emergencies.
    Fri, 29 Feb 2008 20:37:23 GMThttp://www.upmc-cbn.org/report_archive/2008/02_February_2008/cbnreport_022908.html

  2. This Year's flu Season Marked by Vaccine Mismatch in the U.S. and Antiviral Resistance in Europe (02-14-2008)

    CDC reports that this year's flu season in U.S. is more severe than past 2 and that vaccine does not match 43% of strains circulating in U.S. In Europe, there are reports of unexplained oseltamivir resistance.
    Thu, 14 Feb 2008 20:55:53 GMThttp://www.upmc-cbn.org/report_archive/2008/02_February_2008/cbnreport_02142008.html

  3. Progress Toward the Development of a Universal Influenza Vaccine (02-01-2008)

    Acambis , a vaccine development company, announced positive preliminary results from two studies of its universal influenza vaccine, ACAM-FLU-A
    Fri, 01 Feb 2008 15:26:45 GMThttp://www.upmc-cbn.org/report_archive/2008/02_February_2008/cbnreport_02012008.html

  
January 2008

CBN January 2008

Clinicians' Biosecurity Network Report archive for January 2008.

  1. WHO Update on Human H5N1 Infections (01-18-2008)

    WHO Committee Human Infection with Avian Influenza A (H5N1) Virus provides updated information on human cases of highly pathogenic avian influenza A (H5N1) infection.
    Tue, 22 Jan 2008 15:00:49 GMThttp://www.upmc-cbn.org/report_archive/2008/01_January_2008/cbnreport_01182008

  2. Ten Notable Publications of 2007 (01-10-2008)

    Ten notable publications of 2007 from Center for Biosecurity of UPMC.
    Thu, 10 Jan 2008 17:47:46 GMThttp://www.upmc-cbn.org/report_archive/2008/01_January_2008/cbnreport_01102008.html

  
December 2007

CBN December 2007

Clinicians' Biosecurity Network Report archive for December 2007.

  1. Evidence for a Heritable Predisposition to Fatal Influenza (12-19-2007)

    CBN Report: A recent study by Albright and colleagues from the University of Utah School of Medicine supports the hypothesis that there exists an inherited predisposition to developing and dying from severe influenza.
    Wed, 19 Dec 2007 18:39:00 GMThttp://www.upmc-cbn.org/report_archive/2007/12_December_2007/cbnreport_12192007.html

  2. Estimate of the Financial Effect of a Flu Pandemic on U.S. Hospitals (12-07-2007)

    CBN Report: Center for Biosecurity estimates potential financial impact of a flu pandemic on U.S. hospitals to be approximately $785,000 for average U.S. hospital, and $3.9 billion total for all U.S. hospitals.
    Fri, 07 Dec 2007 18:37:25 GMThttp://www.upmc-cbn.org/report_archive/2007/12_December_2007/cbnreport_12072007

   
November 2007

CBN November 2007

Clinicians' Biosecurity Network Report archive for November 2007.

  1. National Academies Report on Boston BSL-4 Laboratory (11-30-2007)

    Yesterday, a National Research Council (NRC) committee deemed an NIH risk analysis for a proposed biocontainment laboratory at Boston University to be "not sound and credible."
    Fri, 30 Nov 2007 21:37:00 GMThttp://www.upmc-cbn.org/report_archive/2007/11_November_2007/cbnreport_11302007.html

  2. Oseltamivir Reduces Mortality in Patients Hospitalized with Influenza (11-15-2007)

    CBN Report: In study by McGeer et al, oseltamivir therapy administered to adult patients hospitalized with influenza decreased mortality by almost 80%.
    Thu, 15 Nov 2007 13:50:29 GMThttp://www.upmc-cbn.org/report_archive/2007/11_November_2007/cbnreport_11152007.html

  3. Drug-Resistant H5N1 Influenza Viruses May Retain Fitness (11-01-2007)

    CBN Report: A study by Yen of Robert Webster's lab at St. Jude's Hospital reveals that some mutations of H5N1 conferring neuraminidase inhibitor resistance do not lead to loss of viral fitness.
    Thu, 01 Nov 2007 19:32:22 GMThttp://www.upmc-cbn.org/report_archive/2007/11_November_2007/cbnreport_11012007.html

   
October 2007

CBN October 2007

Clinicians' Biosecurity Network Report archive for October 2007.

  1. White House Releases HSPD 21: National Strategy for Public Health and Medical Preparedness (10-19-2007)

    This directive addresses preparedness for catastrophic health events . . . which result in a number of ill or injured persons sufficient to overwhelm the capabilities of immediate local and regional emergency response and health care systems.
    Mon, 22 Oct 2007 18:54:05 GMThttp://www.upmc-cbn.org/report_archive/2007/10_October_2007/cbnreport_10192007.html

  2. Recent H5N1 Developments (10-15-2007)

    CBN Report: Recent articles shed light on the virulence and pathogenesis of H5N1 and suggest a possible new approach to treatment.
    Mon, 15 Oct 2007 15:21:54 GMThttp://www.upmc-cbn.org/report_archive/2007/10_October_2007/cbnreport_10152007.html

  3. IOM Releases Pandemic PPE Report (10-04-2007)

    CBN Report: IOM released a report entitled, "Preparing for an Influenza Pandemic: PPE for Healthcare Workers" stating that the regulatory, certification, and evaluation requirements for PPE need to be revisited to ensure PPE are safe and effective.
    Thu, 04 Oct 2007 20:00:05 GMThttp://www.upmc-cbn.org/report_archive/2007/10_October_2007/cbnreport_10042007.html
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