Topics in Clinical Biosecurity: Biothreat Agents

                             
 Listed below are all CBN* articles on Biothreat Agents published since 2005

• 01/17/2012. Clinicians' Biosecurity Resource App Now Available: The CBR is a healthcare provider’s guide to clinical features, diagnostic tests, treatments, and infection control measures for the most dangerous potential biothreats. It is available for download at no charge from the iTunes App store. 
• 11/18/2011. Analysis of 21 Years’ Data on Melioidosis Pneumonia Patient Outcomes: This analysis of long-term patient outcome data offers insight into clinical presentation and management of melioidosis, which is caused by category B agent Burkholderia pseudomallei, and is, where endemic, a common cause of community acquired pneumonia. 
• 09/02/2011. Anthrax-like Disease Caused by Bacillus cereus: A man in Texas recently died of an anthrax-like illness that was caused by a toxin-producing strain of B. cereus. Of the Bacillus species known to cause human disease, only B. anthracis is generally recognized as capable of causing fulminant disease. 
• 08/05/2011. Invasion of Red Blood Cells by Francisella tularenesis: Although F. tularensis is known to invade other cell types in addition to phagocytes, the susceptibility of erythrocytes (RBCs)—the most numerous cell in the blood—to infection with this bacteria is not known. 
• 06/06/2011. E. coli Infection and Hemolytic-uremic Syndrome: On May 27, 2011, the World Health Organization (WHO) announced that Germany was investigating an unusually large outbreak of hemolytic-uremic syndrome (HUS). The causative agent is an uncommon and especially virulent strain of the bacterium E. coli. 
• 05/06/2011. Absence of Smallpox "Take" May Not Indicate Revaccination Failure: Successful vaccination against smallpox is generally determined by inspection of the vaccine site approximately one week after vaccination. It has long been observed that people who are revaccinated have lower rates of vaccine takes. 
• Lassa Fever in Philadelphia. October 8, 2010. 
• Hundreds of Cutaneous Anthrax Cases in Bangladesh. September 15, 2010. 
• Typhoid Fever: A Reemerging Threat? September 3, 2010. 
• Is Rift Valley Fever Virus a Real Risk for the United States? July 30, 2010. 
• Anthrax Cases Among Heroin Users in Europe Illustrate Novel Risk. January 21, 2010. 
• Unusual Case of GI Anthrax in New Hampshire Raises Questions. January 7, 2010. 
• 3rd Generation Smallpox Vaccine LC16m8 Proved Safe and Immunogenic. March 20, 2009. 
• Longer Treatment Window for Botulism. February 20, 2009. 
• Update on Smallpox Vaccine. January 8, 2009 
• Long-lived Immunity after Smallpox Vaccination. December 5, 2008. 
• New Arenavirus Identified as Cause of Cluster of Illness and Death in South Africa and Zambia. November 7, 2008. 
• Atypical Presentation of Cutaneous Tularemia. June 27, 2008. 
• CDC Publishes Report on Meeting of Experts to Update Guidelines for Management of Anthrax. April 14, 2008. 
• The Use of MedKits to Augment Rapid Distribution of Antibiotics after an Anthrax Attack. March 14, 2008. 
• HHS Award Multiple Contracts for Anthrax Countermeasures. September 28, 2007. 
• Symptoms of Anthrax in Children May be More Varied than Previously Thought. September 14, 2007. 
• New Smallpox Vaccine Licensed. September 7, 2007. 
• Dilution of Smallpox Vaccine, Revisited. March 1, 2007. 
• Immunological Responses after Exposure to Anthrax Spores in the U.S. Capitol, 2001. January 18, 2007. 
• Smallpox Antiviral Effective in Animal Trials. October 23, 2006. 
• Anthrax Appraisal 5 Years Later: Top 10 Accomplishments and Remaining Challenges. September 22, 2006. 
• New Anthrax Countermeasure to be Acquired by HHS. July 20, 2006. 
• Safety and Immunogenicity of the Second Generation Anthrax Vaccine Candidate. June 16, 2006. 
• Large Botulism Outbreak in Thailand. April 21, 2006. 
• Could the Duration of Postexposure Antibiotic Prophylaxis Against Inhalational Anthrax be Shortened? March 17, 2006. 
• Isolated Case of Naturally-Occurring Inhalational Anthrax in a New York City Resident. February 23, 2006. 
• Lab Diagnosis of Y. pestis. December 29, 2005. 
• Anthrax Staging System. November 8, 2005. 
• Anthrax Vaccine Candidate. July 13, 2005. 
• Potential Anthrax Therapeutic. July 11, 2005. 
• Ebola, Marburg Vaccine. June 14, 2005. 
• Disease Reporting Rules; Anthrax Anti-toxin. June 6, 2005. 
• Ebola; Pandemic Influenza. May 31, 2005. 
• Anthrax Meningitis. May 9, 2005. 
• Marburg Virus. May 2, 2005. 
• Anthrax Response; New Vaccines. April 26, 2005. 
• Marburg Situation Worsens. April 12, 2005. 
• Airborne spread of SARS; Marburg outbreak. April 6, 2005. 

                  
*Formerly The Clinicians' Biosecurity Network Report; title changed in July 2011